A conserved abundant cytoplasmic long noncoding RNA modulates repression by Pumilio proteins in human cells
Ailone Tichon, Noa Gil, Yoav Lubelsky, Tal Havkin Solomon, Doron Lemze, Shalev Itzkovitz, Noam Stern-Ginossar, Igor Ulitsky
The paper identifies NORAD, a conserved cytoplasmic lncRNA, and shows it modulates PUM1 and PUM2 to regulate mRNA levels of genes involved in chromosome segregation.
bioRxiv · Mar 21, 2016Molecular Biology