Yoav Lubelsky

The paper shows that ASOs targeting CHASERR induce fusion transcripts that increase CHD2 expression, alleviating haploinsufficiency in mice.

This study identifies a mechanism by which RFX1 regulates target genes through its interaction with PP1c, recruiting the phosphatase to promoters to modulate transcription factors and RNA Polymerase II.

The paper identifies Alu repeat-derived sequences that drive nuclear localization of long RNAs by binding HNRNPK, showing conservation across species.

The paper identifies NORAD, a conserved cytoplasmic lncRNA, and shows it modulates PUM1 and PUM2 to regulate mRNA levels of genes involved in chromosome segregation.