Incomplete inhibition of HIV infection results in more HIV infected lymph node cells by reducing cell death
Laurelle Jackson, Jessica Hunter, Sandile Cele, Isabella A.T.M. Ferreira, Andrew C. Young, Farina Karim, Rajhmun Madansein, Kaylesh Jay Dullabh, Chih-Yuan Chen, Noel J. Buckels, Yashica Ganga, Khadija Khan, Mikaël Boullé, Gila Lustig, Richard A. Neher, Alex Sigal
The paper shows that partial inhibition of HIV transmission can increase live infected lymph node cells by reducing cell death, even with fewer HIV DNA copies per cell.
eLife · Mar 19, 2018Peer-reviewedBioinformatics