Author

Isabella A.T.M. Ferreira

Weill Cornell MedicineORCID 0000-0001-5232-4670Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Ana Rafaela TeixeiraiD· 3 shared Cíntia BittariD· 3 shared Marina F. CaskeyiD· 3 shared Michel C. NussenzweigiD· 3 shared Noemi LindeniD· 3 shared Gabriela S. Silva SantosiD· 2 shared Mila JankovićiD· 2 shared Richard Brad JonesiD· 2 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersImmunology

Ana Rafaela TeixeiraORCID

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Author profile →

4 papers

Recent·Most cited

Dynamic Antigen Expression and Intrinsic CTL Resistance in HIV Reservoir Clones

Isabella A. T. M. Ferreira, Alberto Herrera, Tan Thinh Huynh, Nathan L. Board, Emily Stone, Noemi Linden, Yanqin Ren, Cíntia Bittar, Virender Kumar Pal, Shane Vedova, Ethan Naing, Parul Sinha, Ali Danesh, Cristian Ovies, Fitty L Liu, , Richard Brad Jones

This study characterizes HIV reservoir clones and shows they can be culled by sustained CTL pressure, with some displaying intrinsic resistance linked to low oxidative stress.

bioRxiv · Feb 23, 2026 · PreprintImmunology

HIV-1 expression is heterogeneous among clones of CD4+ T cells carrying authentic intact latent proviruses

Cíntia Bittar, Ana Rafaela Teixeira, Thiago Y. Oliveira, Gabriela S. Silva Santos, Klara Lenart, Marcílio Jorge Fumagalli, Noemi Linden, Isabella A.T.M. Ferreira, Marina F. Caskey, R. Brad Jones, Mila Janković, Michel C. Nussenzweig

The paper examines HIV-1 expression in CD4+ T cell clones with latent proviruses, finding heterogeneous expression and limited response to latency reversing agents.

bioRxiv · Aug 5, 2025 · PreprintImmunology

Transcription of HIV-1 at sites of intact latent provirus integration

Ana Rafaela Teixeira, Cíntia Bittar, Gabriela S. Silva Santos, Thiago Y. Oliveira, Amy S. Huang, Noemi Linden, Isabella A.T.M. Ferreira, Tetyana Murdza, Frauke Muecksch, Richard Brad Jones, Marina F. Caskey, Mila Janković, Michel C. Nussenzweig

This study examines transcription of HIV-1 at sites of intact latent provirus integration in T cells, finding that latent proviral promoters are significantly less active than in productively infected cells and have minimal impact on neighboring gene expression.

The Journal of Experimental Medicine · Jul 31, 2024Peer-reviewedImmunology

Incomplete inhibition of HIV infection results in more HIV infected lymph node cells by reducing cell death

Laurelle Jackson, Jessica Hunter, Sandile Cele, Isabella A.T.M. Ferreira, Andrew C. Young, Farina Karim, Rajhmun Madansein, Kaylesh Jay Dullabh, Chih-Yuan Chen, Noel J. Buckels, Yashica Ganga, Khadija Khan, Mikaël Boullé, Gila Lustig, Richard A. Neher, Alex Sigal

The paper shows that partial inhibition of HIV transmission can increase live infected lymph node cells by reducing cell death, even with fewer HIV DNA copies per cell.

eLife · Mar 19, 2018Peer-reviewedBioinformatics