Author

Farina Karim

Africa Health Research InstituteORCID 0000-0001-9698-016XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alex SigaliD· 2 shared Gila LustigiD· 2 shared Khadija KhaniD· 2 shared Sandile CeleiD· 2 shared Yashica GangaiD· 2 shared Ace Carstens· 1 shared Alaina Olson· 1 shared Alasdair J. LeslieiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

Alex SigalORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologyNature CommunicationsPeer-reviewedJul 25, 2026

Inflammatory Biomarkers of Asymptomatic and Symptomatic Tuberculosis

Denis Awany, Dominique T Ariefdien, Simon C. Mendelsohn…·Petrus Tyambetyuv

This study identifies transcriptomic and proteomic features of asymptomatic tuberculosis, revealing distinct sub-clusters and a new blood signature, but finds weaker diagnostic performance for asymptomatic cases compared to symptomatic ones.

DOI 10.1038/s41467-026-75909-6

humanbulk RNA-seq

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MicrobiologybioRxivPreprintMar 25, 2019

The CNS in the face of ART contains T cell origin HIV which can lead to drug resistance

Gila Lustig, Sandile Cele, Farina Karim…·Alex Sigal

The paper investigates the origin of HIV in the CNS of ART-suppressed individuals and finds T cell-derived HIV that can lead to drug resistance.

DOI 10.1101/588426

humanbulk RNA-seq

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BioinformaticseLifePeer-reviewedMar 19, 2018

Incomplete inhibition of HIV infection results in more HIV infected lymph node cells by reducing cell death

Laurelle Jackson, Jessica Hunter, Sandile Cele…·Alex Sigal

The paper shows that partial inhibition of HIV transmission can increase live infected lymph node cells by reducing cell death, even with fewer HIV DNA copies per cell.

12 citations

humanstatistical model

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