Author

Mikaël Boullé

Africa Health Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

Alex SigaliD· 2 shared Andrew C. YoungiD· 1 shared Anna K. CoussensiD· 1 shared Chih-Yuan Chen· 1 shared Farina KarimiD· 1 shared Frank BrombacheriD· 1 shared Gila LustigiD· 1 shared Isabella A.T.M. FerreiraiD· 1 shared

Activity by Year

2018-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Alex SigalORCID

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2 papers

Recent·Most cited

Molecular BiologyFrontiers in Cellular and Infection MicrobiologyPeer-reviewedAug 3, 2018

Viral apoptosis evasion via the MAPK pathway by use of a host long noncoding RNA

Samantha Barichievy, Jerolen Naidoo, Mikaël Boullé…·Musa M. Mhlanga

This study shows HIV-1 evades apoptosis in macrophages by manipulating the MAP2K1/ERK2 pathway to dysregulate lincRNA-p21, and suggests MAP2K1/ERK2 inhibitors as a therapeutic strategy.

40 citations

humanDNA methylation

𝕏 PostBluesky

BioinformaticseLifePeer-reviewedMar 19, 2018

Incomplete inhibition of HIV infection results in more HIV infected lymph node cells by reducing cell death

Laurelle Jackson, Jessica Hunter, Sandile Cele…·Alex Sigal

The paper shows that partial inhibition of HIV transmission can increase live infected lymph node cells by reducing cell death, even with fewer HIV DNA copies per cell.

12 citations

humanstatistical model

𝕏 PostBluesky