Organoid single-cell profiling identifies a transcriptional signature of glomerular disease
Jennifer L. Harder, Rajasree Menon, Edgar A. Otto, Jian Zhou, Sean F. Eddy, Noel L. Wys, Christopher Lund O'Connor, Jinghui Luo, Viji Nair, Cristina Cebrián, Jason R. Spence, Markus Bitzer, Olga G. Troyanskaya, Jeffrey B. Hodgin, Roger C. Wiggins, , Nephrotic Syndrome Study Network (NEPTUNE)
The paper identifies a transcriptional signature of glomerular disease using single-cell profiling of human kidney organoids and validates it in disease cohorts.
JCI Insight · Jan 10, 2019Peer-reviewedSystems Biology