Author

Jennifer L. Harder

University of MichiganORCID 0000-0002-7927-608XUnclaimed ORCID profile · follow to get notified of new preprints

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Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:organoid / primary culture· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Matthias KretzleriD· 2 shared Rajasree MenoniD· 2 shared Viji NairiD· 2 shared Akihiro MinakawaiD· 1 shared Anja M. BillingiD· 1 shared Benjamin FreedmaniD· 1 shared Bradley GodfreyiD· 1 shared Céline C. BerthieriD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCell Biology

Matthias KretzlerORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintJan 14, 2026

Dapagliflozin mitigates hypoxia-induced metabolic stress, kidney tubular cell death and fibrosis

Akihiro Minakawa, Jamal El Saghir, Céline C. Berthier…·Jennifer L. Harder

This study shows dapagliflozin reduces hypoxia-induced metabolic stress, cell death, and fibrosis in kidney organoids derived from human pluripotent stem cells.

1 citation

humanorganoid / primary culture

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Systems BiologyJCI InsightPeer-reviewedJan 10, 2019

Organoid single-cell profiling identifies a transcriptional signature of glomerular disease

Jennifer L. Harder, Rajasree Menon, Edgar A. Otto…·Nephrotic Syndrome Study Network (NEPTUNE)

The paper identifies a transcriptional signature of glomerular disease using single-cell profiling of human kidney organoids and validates it in disease cohorts.

88 citationstop 1%

humanscRNA-seq

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