BioengineeringbioRxivPreprint
Ocular Safety and Efficacy of AAV-mediated Tyrosinase Gene Augmentation in a Nonhuman Primate Model
Jaegook Lim, Alessandra M. Larimer-Picciani, Ala Moshiri…·Sara M. Thomasy
This study evaluates the safety and efficacy of AAV-mediated TYR gene augmentation in nonhuman primates for OCA1 treatment, showing localized hypermelanosis and RPE transduction without severe adverse effects.
DOI 10.64898/2026.07.13.738268