Artefactual formation of pyruvate from in-source conversion of lactate
N. W. Snyder, S. Trefely, C. Mesaros, P. Xu, M. Doan, H. Jiang, O. Altinok, Z. Orynbayeva
The paper identifies an artefactual pyruvate formation from lactate during LC-MS analysis, highlighting the need for improved resolution or quantification in metabolomics studies.
bioRxiv · Apr 23, 2018Biochemistry