Author

O. Burbidge

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

G. Zenkeviciute· 1 shared J. A. Endicott· 1 shared L. Itzhaki· 1 shared M. E. Noble· 1 shared M. W. Pastok· 1 shared S. L. Hodder· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

G. Zenkeviciute

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1 paper

Recent·Most cited

Nanobodies restore stability to cancer-associated mutants of tumor suppressor protein p16INK4a

O. Burbidge, M. W. Pastok, S. L. Hodder, G. Zenkeviciute, M. E. Noble, J. A. Endicott, L. Itzhaki

This paper shows nanobodies stabilize p16INK4a mutants and restore their function by binding to a site distinct from CDK6, enabling ternary complex formation.

bioRxiv · Jul 1, 2021Biochemistry