Reciprocal regulation of TLR4, TLR3 and Macrophage Scavenger Receptor 1 regulates nonopsonic phagocytosis of the fungal pathogen Cryptococcus neoformans.
C. U. Onyishi, G. E. Desanti, A. L. Wilkinson, G. Fejer, O. D. Christophe, C. E. Bryant, S. Mukhopadhyay, S. Gordon, R. C. May
This study identifies MSR1 as a key receptor for nonopsonic phagocytosis of Cryptococcus neoformans and shows TLR4/MSR1 crosstalk in this process.
bioRxiv · Jan 30, 2023 · PreprintMicrobiology