Lack of Adipocyte Purinergic P2Y6 Receptor Greatly Improves Whole Body Glucose Homeostasis
S. Jain, S. P. Pydi, K. S. Toti, B. Robaye, M. Idzko, O. Gavrilova, J. Wess, K. A. Jacobson
This study shows that deleting P2Y6R in adipocytes improves glucose homeostasis and prevents obesity, while deletion in skeletal muscle impairs glucose uptake.
bioRxiv · Apr 3, 2020Physiology