Author

O. Korsgren

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:imaging· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

O. Skog· 2 shared A. Melhus· 1 shared A. S. Deshmukh· 1 shared A. Tegehall· 1 shared A. Wiberg· 1 shared C. Castillejo-Lopez· 1 shared C. Kumar· 1 shared C. Wadelius· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersImmunology

O. Skog

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Illuminating the complete β-cell mass of the human pancreas - signifying a new view on the islets of Langerhans

J. Lehrstrand, W. L. Davies, M. Hahn, O. Korsgren, T. Alanentalo, U. Ahlgren

The paper uses 3D imaging to reveal new heterogeneity in human pancreatic islets, showing 50% lack glucagon-producing cells.

bioRxiv · Nov 15, 2023Cell Biology

A new animal model signifying a decisive bridge between innate immunity and the pathognomonic morphological characteristics of Type 1 Diabetes

A. Tegehall, S. Ingvast, A. Melhus, O. Skog, O. Korsgren

This study develops a rat model of Type 1 Diabetes by inducing inflammation through heat-inactivated bacteria, mimicking human insulitis and immune responses.

bioRxiv · Dec 10, 2021 · PreprintImmunology

Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes and normal tissues

K. Diamanti, M. Cavalli, M. J. Pereira, G. Pan, C. Castillejo-Lopez, C. Kumar, F. Mundt, J. Komorowski, A. S. Deshmukh, M. Mann, O. Korsgren, J. W. Eriksson, C. Wadelius

The paper uses proteomics to compare metabolic pathways across tissues in prediabetes, type 2 diabetes, and normal controls, identifying tissue-specific metabolic dysregulation.

bioRxiv · May 9, 2021Cell Biology

Characterization of the endocrine pancreas in Type 1 Diabetes: islet size is maintained but islet number is markedly reduced

P. Seiron, A. Wiberg, L. Krogvold, F. L. Jahnsen, K. Dahl-Jorgensen, O. Skog, O. Korsgren

This study shows that T1D patients have reduced islet number but similar islet size, with insulin-negative islets dominated by glucagon-positive cells expressing PDX1.

bioRxiv · Nov 29, 2018Pathology