F. L. Jahnsen

Separate Gut Plasma Cell Populations Produce Autoantibodies Against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis

The paper identifies separate gut plasma cell populations in DH patients producing autoantibodies specific to TG2 and TG3 with no cross-reactivity.

Spatiotemporal single cell transcriptomic analyzis of human gut macrophages revealsmultiple functional and niche-specific subsets

The paper identifies multiple functional subsets of gut macrophages using single-cell transcriptomics and shows their niche-specific roles in tissue homeostasis.

The human small intestine contains two subsets of regulatory Foxp3+ CD4+ T cells with very different life span and functional properties.

This study identifies two distinct subsets of Foxp3+ CD4+ Tregs in the human small intestine with different functional properties and lifespans, which expand in celiac disease.

CD4+ T cells persist for years in the human small intestine and mediate robust Th1 immunity.

The paper shows that CD4+ T cells persist in the human small intestine for over a year and are mainly Th1 cells, with implications for gut-targeted vaccines and therapies.

Resident memory CD8 T cells persist for years in human small intestine

The paper identifies that most CD8 T cells in the human small intestine are resident memory cells that persist for over a year and maintain a stable TCR repertoire.

Characterization of the endocrine pancreas in Type 1 Diabetes: islet size is maintained but islet number is markedly reduced

This study shows that T1D patients have reduced islet number but similar islet size, with insulin-negative islets dominated by glucagon-positive cells expressing PDX1.