PathologybioRxivPreprint
Prion-like α-synuclein pathology in the brains of infants: Krabbe disease as a novel seed-competent α-synucleinopathy
C. Hatton, S. S. Ghanem, D. Koss…·D. Erskine
This study shows that α-synuclein in Krabbe disease brains can seed fibrillar aggregates similar to Lewy body diseases, indicating prion-like properties in infants.
DOI 10.1101/2021.10.12.463948