Hepatocyte-specific miR-33 deletion attenuates NAFLD-NASH-HCC progression
P. FERNANDEZ TUSSY, J. Sun, M. P. Cardelo, N. L. Price, L. Goedeke, C. E. Xirouchaki, X. Yang, O. Pastor-Rojo, A. M. Bennett, T. Tiganis, Y. Suarez, C. Fernandez-Hernando
This study shows that deleting miR-33 in hepatocytes reduces NAFLD progression to NASH, fibrosis, and HCC by improving lipid metabolism and mitochondrial function.
bioRxiv · Jan 18, 2023 · PreprintPhysiology