Author

C. E. Xirouchaki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

A. M. Bennett· 2 shared C. Fernandez-Hernando· 2 shared X. Yang· 2 shared A. Lawan· 1 shared B. Qiu· 1 shared J. Sun· 1 shared J.-S. Yi· 1 shared L. Goedeke· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPhysiology

A. M. Bennett

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2 papers

Recent·Most cited

MKP1 promotes nonalcoholic steatohepatitis by suppressing AMPK activity through LKB1 nuclear retention

B. Qiu, A. Lawan, C. E. Xirouchaki, J.-S. Yi, M. Robert, L. Zhang, W. Brown, C. Fernandez-Hernando, X. Yang, A. M. Bennett

This study shows MKP1 suppresses AMPK activity via LKB1 nuclear retention, promoting NASH by inducing hepatocyte death and inflammation.

bioRxiv · Jul 10, 2023Physiology

Hepatocyte-specific miR-33 deletion attenuates NAFLD-NASH-HCC progression

P. FERNANDEZ TUSSY, J. Sun, M. P. Cardelo, N. L. Price, L. Goedeke, C. E. Xirouchaki, X. Yang, O. Pastor-Rojo, A. M. Bennett, T. Tiganis, Y. Suarez, C. Fernandez-Hernando

This study shows that deleting miR-33 in hepatocytes reduces NAFLD progression to NASH, fibrosis, and HCC by improving lipid metabolism and mitochondrial function.

bioRxiv · Jan 18, 2023 · PreprintPhysiology