The central role of the tail in switching off myosin II in cells
R. Craig, S. Yang, K. H. Lee, J. L. Woodhead, O. Sato, M. Ikebe
The paper reveals the structural mechanism by which the tail of myosin II inhibits its activity by interacting with the heads to block ATP hydrolysis, actin binding, and filament formation.
bioRxiv · Apr 11, 2019Cell Biology