Integration of polygenic and gut metagenomic risk prediction for common diseases
Yang Liu, Scott C. Ritchie, Shu Mei Teo, Matti O. Ruuskanen, Oleg Kambur, Qiyun Zhu, Jon G. Sanders, Yoshiki Vázquez‐Baeza, Karin M. Verspoor, Pekka Jousilahti, Leo Lahti, Teemu Niiranen, Veikko V Salomaa, Aki Samuli Havulinna, Rob D. Knight, , Michael Inouye
This study integrates polygenic risk scores and gut metagenomic data to improve prediction of common diseases, showing enhanced predictive performance over conventional risk factors.
Nature Aging · Mar 25, 2024Peer-reviewedGenetic & Genomic Medicine