High-precision CRISPR-Cas9 base editors with minimized bystander and off-target mutations
Jason M. Gehrke, Oliver Cervantes, Kendell Clement, Luca Pinello, J. Keith Joung
This paper evaluates CRISPR-Cas9 base editors to minimize bystander and off-target mutations while improving precision in C-to-T DNA editing.
bioRxiv · Mar 1, 2018 · PreprintMolecular Biology