Cannabidiol prevents the locomotor sensitization induced by cocaine and caffeine and upregulates genes of extracellular matrix and anti-inflammatory pathways in the nucleus accumbens: a transcriptome-wide analysis
José Pedro Prieto, Rafael Sebastián Fort, Guillermo Eastman, Evangelina Coitiño, Oliver Kaminski, Carlos Ferreiro‐Vera, Verónica Sánchez de Medina, Marı́a Ana Duhagon, Cecilia Scorza, José Roberto Sotelo-Silveira
This study shows CBD reduces locomotor sensitization from cocaine and caffeine by upregulating extracellular matrix and anti-inflammatory genes in the nucleus accumbens through transcriptome analysis.
Addiction Neuroscience · Jul 22, 2025Peer-reviewedNeuroscience