José Roberto Sotelo-Silveira

The paper identifies a conserved axonal transcriptome involved in PGE2-induced sensitisation and shows Tnfrsf12a regulates neuronal excitability in DRG neurons.

This study characterizes the soybean TTL gene family, identifies co-expression modules related to abiotic stress, and links TTL proteins to nitrate reductase interactions in nitrogen-fixing plants under water deficit.

The paper examines the gut microbiota of Uruguayan infants during exclusive breastfeeding, linking it to breast milk composition, fecal IgA, and maternal factors, finding delivery mode influences microbiota composition and correlations.

This study uses single-cell RNA sequencing to show that T. cruzi trypomastigote cells express trans-sialidase-like superfamily genes with high heterogeneity and no recurrent combinations.

This paper introduces using Benzonase to generate ribosome footprints for Ribo-seq, simplifying the protocol and reducing time, cost, and bias.

The paper analyzes the evolution of symbiosis in Cupriavidus genus, identifying five distinct lineages and a high conserved symbiotic island with low conservation among plasmids.

The paper investigates seasonal plasticity in neuroendocrine mechanisms of territorial aggression in wild teleost fish, finding elevated androgen and estrogen-related gene expression in non-breeding seasons.

This study shows CBD reduces locomotor sensitization from cocaine and caffeine by upregulating extracellular matrix and anti-inflammatory genes in the nucleus accumbens through transcriptome analysis.

This study shows that deleting Dbc1 in adipocytes does not cause healthy obesity but reveals a role for Dbc1 in inflammation during obesity.

The paper develops a protein structure-based homology search pipeline to annotate kinetoplastid proteins, identifying 23,000 hypothetical proteins and uncovering previously undetected eukaryotic proteins.

This study analyzes soybean root responses to water deficit in nodulated plants using transcriptome and translatome data, identifying gene modules and pathways related to drought tolerance.

The paper investigates the transcriptomic changes in Trypanosoma cruzi epimastigotes with TcUBP1mut knockdown, identifying 276 up- and 426 downregulated genes compared to wildtype.

The paper analyzes transcriptional and translational regulation in Alzheimer's disease model mice to identify gene expression changes and their functional implications.

The paper shows that quantizing nanopore quality scores has minimal impact on downstream analysis and suggests using lossy compression for storage savings.

RENANO improves nanopore FASTQ compression by 39.8% for base call sequences using reference-based methods, with overall improvements of 12.7% in some scenarios.