Marı́a Ana Duhagon

This study uses single-cell RNA sequencing to show that T. cruzi trypomastigote cells express trans-sialidase-like superfamily genes with high heterogeneity and no recurrent combinations.

The paper develops an expression-based annotation strategy to identify and quantify small vault RNAs (svtRNAs) in human cells, showing they are abundant and reproducibly detected across datasets.

This study shows CBD reduces locomotor sensitization from cocaine and caffeine by upregulating extracellular matrix and anti-inflammatory genes in the nucleus accumbens through transcriptome analysis.

The paper analyzes microRNA-mRNA correlations in tissue transcriptomes to identify targeting determinants and provides a bioinformatic tool for predicting interactions.