Parkin overexpression attenuates muscle atrophy and improves mitochondrial bioenergetics but fails to improve key histological features in a mouse model of Duchenne Muscular Dystrophy
Olivier Reynaud, Marie‐Belle Ayoub, Jean‐Philippe Leduc‐Gaudet, Marina Cefis, Marc P. Lussier, Sabah N. A. Hussain, Gilles Gouspillou
This study shows that Parkin overexpression reduces muscle atrophy and improves mitochondrial bioenergetics but does not improve key histological features in a DMD mouse model.
bioRxiv · Jun 13, 2025 · PreprintPhysiology