Jean‐Philippe Leduc‐Gaudet

This study shows that Parkin overexpression reduces muscle atrophy and improves mitochondrial bioenergetics but does not improve key histological features in a DMD mouse model.

The paper examines how physical activity affects mitochondrial function, ROS production, and calcium handling in skeletal muscle across the human lifespan, finding that aging does not reduce mitochondrial respiration but decreases calcium retention capacity.