Tesofensine, a novel antiobesity drug, silences GABAergic hypothalamic neurons
Claudia I. Pérez-Díaz, Jorge Luis-Islas, Axel Lopez, Xarenny Diaz, Omar Molina, Benjamin Arroyo, Mario G. Moreno, Elvi Gil-Lievana, Esmeralda Fonseca, Gilberto Castañeda‐Hernández, Ranier Gutiérrez
This study investigates tesofensine's effects on weight loss and neuronal mechanisms in mice and rats, finding it suppresses appetite and prevents weight rebound.
PLoS ONE · Apr 24, 2024Peer-reviewedNeuroscience