Oxygen availability and hypoxia-independent action of HIF1α controls human trophoblast maturation and function
Johanna Lattner, Javier Bregante, Michaela Burkon, Ornella Elezaj, Meritxell Huch, Michele Marass, Claudia Gerri
This study shows that oxygen levels and HIF1α act independently to regulate human trophoblast maturation and function in organoids.
bioRxiv · Dec 15, 2025 · PreprintDevelopmental Biology