Disruption of membrane cholesterol organization impairs the concerted activity of PIEZO1 channel clusters
P. Ridone, E. Pandzic, M. Vassalli, C. D. Cox, A. Macmillan, P. A. Gottlieb, B. Martinac
This study shows that membrane cholesterol organization is critical for PIEZO1 channel cluster function, affecting their response to mechanical force and synchronization.
bioRxiv · Apr 11, 2019Biophysics