Somatic mutations in CTCF zinc fingers produce cellular phenotypes explained by structure-function relationships
J. E. Rasko, C. G. Bailey, S. Gupta, C. Metierre, P. Amarasekera, P. O'Young, W. Kyaw, T. Laletin, H. Francis, C. Semaan, K. Singh, C. Mullighan, O. Wolkenhauer, U. Schmitz
This study identifies somatic CTCF mutations in cancer and shows how their structure-function relationships affect cellular phenotypes and tumour suppressor function.
bioRxiv · Jan 8, 2021Cancer Biology