The virulence of the Cryptococcus neoformans VNIa-5 lineage is highly plastic and associated with isolate background.
H. P. Trieu, T. L. Thanh, A. V. Duong, T. N. Mai, L. N. P. Huong, G. E. Thwaites, E. Johnson, C. N. V. Vinh, S. Baker, P. Ashton, J. N. Day
The study shows that the virulence of the Cryptococcus neoformans VNIa-5 lineage varies based on isolate source and can be induced through secreted proteins in extracellular vesicles.
bioRxiv · Feb 24, 2020 · PreprintMicrobiology