Author

G. E. Thwaites

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 5 Approach:experimental assay· 4 Organism:human· 3 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:fungi (other)· 1 Assay:metagenomics· 1

Frequent Co-Authors

S. Baker· 3 shared A. V. Duong· 2 shared J. N. Day· 2 shared P. M. Ashton· 2 shared B. Javid· 1 shared C. Anscombe· 1 shared C. Boinett· 1 shared C. Giamberardino· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersMicrobiology

S. Baker

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Rifampicin tolerance and growth fitness among isoniazid-resistant clinical Mycobacterium tuberculosis isolates: an in-vitro longitudinal study

V. Srinivasan, N. L. H. Bao, D. N. Vinh, N. Thanh Hoang Le, D. D. Thu, N. L. Quang, L. P. T. Trieu, H. N. Nhung, V. T. N. Ha, P. V. K. Thai, D. T. M. Ha, N. H. Lan, M. Caws, G. E. Thwaites, B. Javid, N. T. Thuong

This study examines rifampicin tolerance in isoniazid-resistant Mycobacterium tuberculosis isolates, finding increased tolerance and faster growth in resistant strains, which may contribute to multidrug-resistant TB emergence.

bioRxiv · Nov 22, 2023Microbiology

Distribution and origins of Mycobacterium tuberculosis L4 in Southeast Asia

P. M. Ashton, J. Cha, C. Anscombe, N. T. T. Thuong, G. E. Thwaites, T. M. Walker

The paper investigates the distribution of Mycobacterium tuberculosis Lineage 4 in Southeast Asia using genomic data, finding that most L4 sub-clades in the region have no recent European origin and may involve China as an intermediate.

bioRxiv · Aug 1, 2022Microbiology

The virulence of the Cryptococcus neoformans VNIa-5 lineage is highly plastic and associated with isolate background.

H. P. Trieu, T. L. Thanh, A. V. Duong, T. N. Mai, L. N. P. Huong, G. E. Thwaites, E. Johnson, C. N. V. Vinh, S. Baker, P. Ashton, J. N. Day

The study shows that the virulence of the Cryptococcus neoformans VNIa-5 lineage varies based on isolate source and can be induced through secreted proteins in extracellular vesicles.

bioRxiv · Feb 24, 2020 · PreprintMicrobiology

Assessing the virulence of Cryptococcus neoformans causing meningitis in HIV infected and uninfected patients in Vietnam

T. T. Lam, D. Toffaletti, J. Tenor, C. Giamberardino, G. Sempowski, Y. Asfaw, T. H. Phan, A. V. Duong, T. M. Nguyen, L. P. H. Nguyen, C. T. H. Tran, P. M. Ashton, J. Beardsley, C. V. V. Nguyen, G. E. Thwaites, , J. N. Day

This study compares the virulence of Cryptococcus neoformans ST5 and non-ST5 isolates in HIV-infected and uninfected patients in Vietnam, finding ST5 isolates show greater variability and initial inflammatory response but lower fungal burden in mice.

bioRxiv · Feb 19, 2020Microbiology

Ciprofloxacin facilitates the transfer of XDR plasmids from commensal E. coli into epidemic fluoroquinolone-resistant Shigella sonnei

P. T. Pham, T. N. T. Nguyen, D. V. Thuy, H. C. The, F. Alcock, C. Boinett, H. N. D. Thanh, H. T. Tuyen, G. E. Thwaites, M. A. Rabaa, S. Baker

This study tracks the emergence of ciprofloxacin-resistant Shigella sonnei in Vietnam, showing that resistance plasmids are transferred from commensal E. coli via horizontal gene transfer, facilitated by ciprofloxacin use.

bioRxiv · Sep 12, 2019 · PreprintMicrobiology

Pro-Resolving Mediator Profiles And 5-Lipoxygenase Activity In Cerebrospinal Fluid Correlate with Disease Severity and Outcome in Adults with Tuberculous Meningitis

R. A. Colas, N. T. H. Le, T. T. T. Nguyen, E. A. Gomez, L. Ly, T. H. Hai, P. H. Nguyen, M. T. H. Nguyen, G. E. Thwaites, J. Dalli

This study identifies CSF pro-resolving mediator profiles and 5-lipoxygenase activity as correlates of disease severity and 80-day survival in adults with tuberculous meningitis.

bioRxiv · Apr 16, 2019 · PreprintImmunology