Author

P. B. McIntosh

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Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1 Organism:zebrafish· 1

Frequent Co-Authors

A. Borg· 1 shared A. G. Purkiss· 1 shared A. J. Borg· 1 shared A. Nans· 1 shared A. Nawrotek· 1 shared C. P. Earl· 1 shared D. C. Briggs· 1 shared F. M. Houghton· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

A. Borg

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1 paper

Recent·Most cited

A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing

S. Adams, A. G. Purkiss, P. P. Knowles, A. Nans, D. C. Briggs, A. Borg, C. P. Earl, K. M. Goodman, A. Nawrotek, A. J. Borg, P. B. McIntosh, F. M. Houghton, S. Kjaer, N. Q. McDonald

The paper reports crystal and cryo-EM structures of zebrafish RET revealing conformational flexibility and strict geometric spacing in ligand-co-receptor recognition.

bioRxiv · Sep 13, 2020Biophysics