The thrombopoietin receptor agonist eltrombopag inhibits human cytomegalovirus replication via iron chelation
J.-U. Vogel, S. Schmidt, D. Schmidt, F. Rothweiler, B. Koch, P. C. Baer, H. F. Rabenau, D. Michel, T. Stamminger, M. Michaelis, J. Cinatl
This paper shows eltrombopag inhibits HCMV replication via iron chelation, effective against drug-resistant strains and synergistic with ganciclovir.
bioRxiv · Nov 1, 2019Pharmacology & Toxicology