P. Castro-Hartmann

Interplay between Mg2+ and Ca2+ at multiple sites of the ryanodine receptor

The paper determines cryo-EM structures of RyR1 with Mg2+ and identifies multiple Mg2+ binding sites, revealing its inhibitory mechanism and interaction with gating helices.

eIF6 rebinding dynamically couples ribosome maturation and translation

This study shows eIF6 dynamically couples ribosome maturation and translation by sequestering 60S subunits, and its disruption impairs erythropoiesis in mice.