Author

P. Chadebech

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

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F. Pirenne· 1 shared G. Bodivit· 1 shared G. Di Liberto· 1 shared K.-A. Nguyen-Peyre· 1 shared P. Bartolucci· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

F. Pirenne

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1 paper

Recent·Most cited

Soluble LIGHT (TNFSF14) activates endothelial cells, thereby priming the first vessel-occlusive events in acute sickle cell disease

P. Chadebech, K.-A. Nguyen-Peyre, G. Di Liberto, G. Bodivit, F. Pirenne, P. Bartolucci

This study shows that soluble LIGHT levels are elevated in SCD patients during acute crises and promote endothelial activation, leading to platelet and RBC adhesion, which may initiate vaso-occlusion.

bioRxiv · Jun 8, 2023 · PreprintCell Biology