Translational control of TFEB and autophagy via eIF5A rejuvenates B cell immunity
H. Zhang, G. Alsaleh, J. Feltham, Y. Sun, T. Riffelmacher, P. Charles, L. Frau, Z. Yu, S. Mohammed, S. Balabanov, J. Mellor, A. K. Simon
This study identifies a mechanism by which spermidine regulates autophagy through eIF5A-mediated TFEB translation, improving B cell immunity in aging.
bioRxiv · Dec 12, 2018 · PreprintCell Biology