Allosteric coupling between alpha-rings of the 20S proteasome
Z. Yu, Y. Yu, F. Wang, A. G. Myasnikov, P. Coffino, Y. Cheng
The paper shows that ATPase binding at one end of the 20S proteasome allosterically opens the opposite gate, promoting symmetric and asymmetric proteasome configurations.
bioRxiv · Nov 7, 2019Biochemistry