Ketosynthase engineering enhances activity and shifts specificity towards non-native extender units in type I linear polyketide synthase
P. D. Gerlinger, G. Angelidou, N. Paczia, T. J. Erb
This study engineers the ketosynthase domain of a polyketide synthase to enhance activity and shift specificity towards non-native extender units in vitro.
bioRxiv · Feb 16, 2023 · PreprintBiochemistry