MicrobiologybioRxiv
Low affinity membrane transporters can increase net substrate uptake rate by reducing efflux
E. Bosdriesz, M. T. Wortel, J. R. Haanstra…·B. Teusink
The paper investigates why low affinity transporters can increase net substrate uptake by reducing efflux, finding theoretical support and an in silico example in yeast.
DOI 10.1038/s41598-018-23528-7