Author

M. J. Wagner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

A. D. Thompson· 1 shared A. Malhotra· 1 shared A. S. Helms· 1 shared B. L. Prosser· 1 shared B. Teusink· 1 shared D. A. A. Bonin· 1 shared D. E. Ginsburg· 1 shared E. Bosdriesz· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCell Biology

A. D. Thompson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

An unbiased screen identified the Hsp70-BAG3 complex as a regulator of myosin binding protein C3 stability.

A. D. Thompson, M. J. Wagner, J. Rodriguez, A. Malhotra, S. Vander Roest, U. Lilienthal, H. Shao, J. Yob, B. L. Prosser, A. S. Helms, J. E. Gestwicki, D. E. Ginsburg, S. M. Day

A high-throughput compound screen identified JG98 and parthenolide as reducing MyBP-C levels, revealing the Hsp70-BAG3 complex as a regulator of MyBP-C stability in HCM.

bioRxiv · Oct 8, 2022Cell Biology

Oncogenic role of a developmentally regulated NTRK2 splice variant

S. S. Pattwell, S. Arora, N. Nuechterlein, M. Zager, K. R. Loeb, P. J. Cimino, N. C. Holland, N. Reche-Ley, H. Bolouri, D. A. A. Bonin, F. Szulzewsky, V. V. Phadnis, T. Ozawa, M. J. Wagner, M. C. Haffner, , E. C. Holland

The paper identifies TrkB.T1, an embryonic NTRK2 splice variant, as an oncogenic driver in multiple tumor types across species, with distinct interactors in developmental and oncogenic pathways.

bioRxiv · Jan 7, 2022 · PreprintCancer Biology

Low affinity membrane transporters can increase net substrate uptake rate by reducing efflux

E. Bosdriesz, M. T. Wortel, J. R. Haanstra, M. J. Wagner, P. de la Torre Cortes, B. Teusink

The paper investigates why low affinity transporters can increase net substrate uptake by reducing efflux, finding theoretical support and an in silico example in yeast.

bioRxiv · Nov 2, 2017Microbiology