M. T. Wortel

Density-dependent feedback limits the spread of a beta-lactamase mutant: experimental observations and population dynamic model

The paper investigates how cell density and antibiotic concentration affect the spread of beta-lactamase mutants, showing that density determines whether a resistant strain outcompetes or coexists with a susceptible strain.

Population bottleneck has only marginal effect on fitness evolution and its repeatability in dioecious C. elegans

This study tests if population bottlenecks reduce fitness evolution repeatability in C. elegans, finding no significant effect despite reduced genetic diversity.

Evolutionary coexistence in a fluctuating environment by specialization on resource level

The paper investigates whether evolutionary branching can create diversity or destabilize coexistence in microbial communities under fluctuating nutrient levels, finding evidence for evolutionarily stable coexistence.

Continual evolution through coupled fast and slow feedbacks

This paper presents a theoretical framework to identify minimal conditions for continual evolution driven by coupled fast and slow feedbacks, applicable to various systems and population types.

Low affinity membrane transporters can increase net substrate uptake rate by reducing efflux

The paper investigates why low affinity transporters can increase net substrate uptake by reducing efflux, finding theoretical support and an in silico example in yeast.