Author

P. De-la-Torre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

D. Choudhary· 2 shared M. Sotomayor· 2 shared R. Araya-Secchi· 2 shared Y. Narui· 2 shared B. L. Neel· 1 shared C. Chen· 1 shared C. F. Klanseck· 1 shared E. Tamilselvan· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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2 shared papersBiophysics

D. Choudhary

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2 papers

Recent·Most cited

Structural determinants of protocadherin-15 elasticity and function in inner-ear mechanotransduction

D. Choudhary, Y. Narui, B. L. Neel, L. N. Wimalasena, C. F. Klanseck, P. De-la-Torre, C. Chen, R. Araya-Secchi, E. Tamilselvan, M. Sotomayor

This study reports the structure of PCDH15 and its interactions with CDH23, revealing how its ectodomain functions as a gating spring in inner-ear mechanotransduction.

bioRxiv · Jul 8, 2019 · PreprintBiophysics

A Mechanically Weak Extracellular Membrane-Adjacent Domain Induces Dimerization of Protocadherin-15

P. De-la-Torre, D. Choudhary, R. Araya-Secchi, Y. Narui, M. Sotomayor

This study reports the crystal structure of PCDH15's MAD12 domain, showing it induces parallel dimerization and is mechanically weak, with implications for related cadherins.

bioRxiv · Nov 2, 2018Biophysics