Author

P. DePaola

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

c. sun· 1 shared H. Zhou· 1 shared K. LeGault· 1 shared K. Seed· 1 shared k. zhou· 1 shared L. Jiang· 1 shared M. R. Sawaya· 1 shared T. Hillyer· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

c. sun

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cryo-EM structure of amyloid fibril formed by α-synuclein familial A53E mutation

L. Jiang, c. sun, k. zhou, P. DePaola, W. S. Shin, T. Hillyer, M. R. Sawaya, H. Zhou

The paper presents a cryo-EM structure of α-synuclein fibrils with the A53E mutation, showing structural differences that may affect aggregation kinetics and disease progression.

bioRxiv · Mar 11, 2022 · PreprintBiophysics

A phage parasite deploys a nicking nuclease effector to inhibit replication of its viral host

K. LeGault, Z. Barth, P. DePaola, K. Seed

This study identifies a phage-encoded nuclease, NixI, that inhibits replication of its viral host ICP1 by nicking its genome, preventing efficient packaging.

bioRxiv · Jul 12, 2021Microbiology