Author

P. Dirks

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Paleontology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Nikolic· 2 shared M. Gallo· 2 shared A. Bobyn· 1 shared A. Brewer Gillham· 1 shared A. Fuentes· 1 shared A. Gurtov· 1 shared A. H. Luchman· 1 shared A. Kruger· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCancer Biology

A. Nikolic

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Author profile →

3 papers

Recent·Most cited

Evidence for deliberate burial of the dead by Homo naledi

L. R. Berger, T. Makhubela, K. Molopyane, A. Kruger, P. Randolph-Quinney, M. Elliott, B. Peixotto, A. Fuentes, P. Tafforeau, V. Beyrand, K. Dollman, Z. Jinnah, A. Brewer Gillham, K. Broad, J. Brophy, , J. Hawks

This study presents evidence for deliberate burial of Homo naledi remains in South Africa's Rising Star cave system, suggesting mortuary behavior in this species.

bioRxiv · Jun 1, 2023 · PreprintPaleontology

macroH2A2 shapes chromatin accessibility at enhancer elements in glioblastoma to modulate a targetable self-renewal epigenetic network

A. Nikolic, A. Bobyn, F. Maule, K. Ellestad, X. Lun, M. Johnston, C. Gafuik, F. Zemp, S. Paik, N. Ninkovic, S. Marhon, P. Mehdipour, Y. Shen, D. Berger, D. Brownsey, , M. Gallo

This study identifies macroH2A2 as a regulator of chromatin accessibility at enhancers in glioblastoma, showing that inhibiting Menin increases macroH2A2 and represses self-renewal.

bioRxiv · Feb 23, 2021 · PreprintCancer Biology

Single-cell chromatin accessibility in glioblastoma delineates cancer stem cell heterogeneity predictive of survival

P. Guilhamon, M. M. Kushida, A. Nikolic, D. Singhal, G. MacLeod, S. A. M. Tonekaboni, F. M. Cavalli, C. Arlidge, N. Rajakulendran, N. Rastegar, X. Hao, R. Hassam, L. J. Smith, H. Whetstone, F. J. Coutinho, , M. Lupien

The paper uses single-cell chromatin accessibility to identify distinct glioblastoma stem cell states predictive of patient survival.

bioRxiv · Mar 13, 2020 · PreprintCancer Biology