Author

S. Paik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

H. Lee· 2 shared M. Gallo· 2 shared A. Bobyn· 1 shared A. Kim· 1 shared A. Nikolic· 1 shared B. C. Cho· 1 shared B. Carreno· 1 shared C. Gafuik· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

H. Lee

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

In vitro validation of neoantigen prediction algorithm for developing personalized cancer vaccine therapy

Y.-j. Choe, E. Kim, J. Oh, M. Jang, W. Fu, H. Lee, M. Jung, K.-H. Pyo, C.-B. Synn, S. Kim, Y. Yang, A. Kim, B. C. Cho, H. S. Kim, S. Kim, , S. Paik

The paper validates a neoantigen prediction algorithm, Neopepsee, by testing its immunogenicity using ELISpot assays on patient-derived samples and compares it to pVACseq.

bioRxiv · Dec 12, 2021 · PreprintImmunology

macroH2A2 shapes chromatin accessibility at enhancer elements in glioblastoma to modulate a targetable self-renewal epigenetic network

A. Nikolic, A. Bobyn, F. Maule, K. Ellestad, X. Lun, M. Johnston, C. Gafuik, F. Zemp, S. Paik, N. Ninkovic, S. Marhon, P. Mehdipour, Y. Shen, D. Berger, D. Brownsey, , M. Gallo

This study identifies macroH2A2 as a regulator of chromatin accessibility at enhancers in glioblastoma, showing that inhibiting Menin increases macroH2A2 and represses self-renewal.

bioRxiv · Feb 23, 2021 · PreprintCancer Biology

Immunotherapy efficacy in colorectal cancer is dependent on activation of a microbial-metabolite-immune circuit

L. Mager, R. Burkhard, N. Cooke, K. Brown, H. Ramay, S. Paik, J. Stagg, R. Grooves, M. Gallo, I. Lewis, M. Geuking, K. McCoy

This study identifies specific gut bacteria and the metabolite inosine that enhance immunotherapy efficacy in colorectal cancer by promoting Th1 cell activation through the adenosine A2A receptor.

bioRxiv · Feb 26, 2020 · PreprintCancer Biology

Loss of BubR1 Acetylation instigates Replication Stress leading to Complex Chromosomal Rearrangement in tumors

J. Park, S.-Y. Yeu, S. Paik, J. Lee, J. Jang, S. Lee, Y.-I. Koh, H. Lee

This study shows that loss of BubR1 acetylation causes replication stress and complex chromosomal rearrangements in tumors.

bioRxiv · Aug 30, 2019 · PreprintCancer Biology