BiochemistrybioRxivPreprint
Nigratine as first-in-class dual inhibitor of necroptosis and ferroptosis regulated cell death
C. DELEHOUZE, A. COMTE, M. HAUTEVILLE…·S. BACH
This study identifies nigratine as a first-in-class dual inhibitor of necroptosis and ferroptosis, showing efficacy against both cell death pathways with sub-micromolar EC50 values.
DOI 10.1101/2020.12.15.422885