Genome sequence of a diabetes-prone desert rodent reveals a mutation hotspot around the ParaHox gene cluster
A. D. Hargreaves, L. Zhou, J. Christensen, F. Marletaz, S. Liu, F. Li, P. G. Jansen, E. Spiga, M. T. Hansen, S. V. Horn Pedersen, S. Biswas, K. Serikawa, B. A. Fox, W. R. Taylor, J. F. Mulley, , P. W. H. Holland
The paper sequences the genome of a diabetes-prone desert rodent and identifies a mutation hotspot around the ParaHox gene cluster, including the Pdx1 gene, showing extreme divergence due to GC-biased mutation.
bioRxiv · Dec 17, 2016Evolutionary Biology