Saturated Fat Impairs Circadian Transcriptomics through Histone Modification of Enhancers
N. J. Pillon, L. Sardon Puig, A. Altintas, P. G. Kamble, S. Casani-Galdon, B. M. Gabriel, R. Barres, A. Conesa, A. V. Chibalin, E. Naslund, A. Krook, J. R. Zierath
The paper shows that palmitate disrupts circadian transcriptomic rhythmicity in skeletal muscle by altering histone H3K27ac modification of enhancers.
bioRxiv · Feb 23, 2021 · PreprintPhysiology