Author

N. J. Pillon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 5 Cell Biology· 1

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Organism:human· 5 Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 3 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Assay:proteomics· 2

Frequent Co-Authors

J. R. Zierath· 5 shared A. Krook· 4 shared B. M. Gabriel· 4 shared L. Sardon Puig· 3 shared R. Barres· 3 shared A. Altintas· 2 shared L. Dollet· 2 shared A. Conesa· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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5 shared papersPhysiology

J. R. Zierath

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Author profile →

6 papers

Recent·Most cited

Downregulation of NR4A3 during inactivity alters glucose metabolism and impairs translation in human skeletal muscle

J. A. Smith, B. M. Gabriel, A. M. Abdelmoez, M. Savikj, S. C. Wright, S. Koutsilieri, R. Barres, V. M. Lauschke, A. Krook, J. R. Zierath, N. J. Pillon

This study shows that reduced NR4A3 levels in skeletal muscle due to inactivity impair glucose metabolism, translation, and myotube size by affecting mTORC1 and ribosomal pathways.

bioRxiv · Mar 11, 2024 · PreprintCell Biology

Pannexin 3 deletion reduces fat accumulation and inflammation in a sex-specific manner

C. B. Wakefield, V. R. Lee, D. Johnston, P. Boroumand, N. J. Pillon, S. Sayedyahossein, B. L. O'Donnell, J. Tang, R. E. Sanchez-Pupo, K. J. Barr, R. Gros, L. E. Flynn, N. Borradaile, A. Klip, F. Beier, S. Penuela

This study shows that PANX3 deletion reduces fat mass and inflammation in male mice but not females, with male KOs having fewer adipocytes and lower inflammatory gene expression.

bioRxiv · May 4, 2021Physiology

Disrupted circadian core-clock oscillations in Type 2 Diabetes are linked to altered rhythmic mitochondrial metabolism

B. M. Gabriel, A. Altintas, J. A. B. Smith, L. Sardon Puig, X. Zhang, A. Linde Basse, R. C. Laker, H. Gao, Z. Liu, L. Dollet, J. T. Treebak, A. Zorzano, Z. Huo, M. Ryden, J. T. Lanner, , J. R. Zierath

bioRxiv · Feb 24, 2021Physiology

Saturated Fat Impairs Circadian Transcriptomics through Histone Modification of Enhancers

N. J. Pillon, L. Sardon Puig, A. Altintas, P. G. Kamble, S. Casani-Galdon, B. M. Gabriel, R. Barres, A. Conesa, A. V. Chibalin, E. Naslund, A. Krook, J. R. Zierath

The paper shows that palmitate disrupts circadian transcriptomic rhythmicity in skeletal muscle by altering histone H3K27ac modification of enhancers.

bioRxiv · Feb 23, 2021 · PreprintPhysiology

The methylome and comparative transcriptome after high intensity sprint exercise in human skeletal muscle

M. F. Maasar, D. C. Turner, P. P. Gorski, R. A. Seaborne, J. A. Strauss, S. O. Shepherd, M. Cocks, N. J. Pillon, J. R. Zierath, A. T. Hulton, B. Drust, A. P. Sharples

This study examines the methylome and transcriptome changes in human skeletal muscle after high-intensity sprint exercise, finding that change of direction exercise causes greater epigenetic and gene expression changes than straight line sprinting.

bioRxiv · Sep 11, 2020 · PreprintPhysiology

Transcriptomic Profiling of Skeletal Muscle Adaptations to Exercise and Inactivity

N. J. Pillon, B. M. Gabriel, L. Dollet, J. Smith, L. Sardon Puig, J. Botella, D. J. Bishop, A. Krook, J. R. Zierath

This study uses meta-analysis of 66 datasets to identify gene expression changes in skeletal muscle due to exercise and inactivity, highlighting NR4A3 as a key responsive gene.

bioRxiv · Oct 22, 2019Physiology